导师信息#中国科学技术大学化学专业研究生导师介绍#汤朝晖

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汤朝晖单位咨询QQ、微信：2544906，主持；2. 中国科学院青年创新促进会优秀会员，2015年，优秀会员人才专项经费，150万元，主持；3. 国家自然科学基金面上项目，51373168，物理化学性质和肿瘤种类对高分子纳米粒子在小鼠体内代谢和分布的影响研究，2014/01–2017/12，80万元，主持；4. 国家科技重大专项重大新药创制，2014ZX09507-009，IPT-ZHW155的临床前研究，2014/01–2016/12，40.5万元，参加（子课题副组长）；5. 吉林省医药产业发展专项资金项目，20130727050YY，聚谷氨酸接枝聚乙二醇药用辅料及顺铂胶束制剂的研究和开发，2013/06–2016/05，50万元，主持；6. 国家科技重大专项重大新药创制，2013ZX09J13110-11B，基于生物可降解高分子电纺丝技术的战伤救治药物体系，2013/01–2015/12，110万元参加（子课题副组长）；7. 吉林省科技发展计划项目，科技支撑计划，重点科技攻关项目，20130206066GX，用于抗肿瘤药物靶向控释的高分子载体材料的研究和开发，2013/01–2015/12，18万元，主持；8. 国家自然科学基金面上项目，51173184，氧化还原和pH双敏感的纳米药物控释系统及其克服肿瘤多药耐药性研究，2012/01–2015/12，65万元，主持；9. 中国科学院青年创新促进会会员，2011年，会员人才专项经费，40万元，主持；10. 国家自然科学青年基金，2009年，具有生物分子识别功能可生物降解高分子材料的合成与应用，23万元，主持。学术论文与书籍章节目录[1]Y.Zhang,C.Xiao,J.Ding,M.Li,X.Chen,Z.Tang,X.Zhuang,X.Chen,Acomparativestudyoflinear,Y-shapedandlinear-dendriticmethoxypoly(ethyleneglycol)-block-polyamidoamine-block-poly(l-glutamicacid)blockcopolymersfordoxorubicindeliveryinvitroandinvivo,ActaBiomater.40(2016)243-253.[2]H.Yu,Z.Tang,M.Li,W.Song,D.Zhang,Y.Zhang,Y.Yang,H.Sun,M.Deng,X.Chen,Cisplatinloadedpoly(L-glutamicacid)-g-methoxypoly(ethyleneglycol)complexnanoparticlesforpotentialcancertherapy:preparation,invitroandinvivoevaluation,JBiomedNanotechnol.12(1)(2016)69-78.[3]Y.Wang,S.Lv,M.Deng,Z.Tang,X.Chen,Acharge-conversionalintracellular-activatedpolymericprodrugfortumortherapy,Polym.Chem.7(2016)2253-2263.[4]Z.Tang,C.He,H.Tian,J.Ding,B.S.Hsiao,B.Chu,X.Chen,Polymericnanostructuredmaterialsforbiomedicalapplications,Prog.Polym.Sci.60(2016)86-128.[5]W.Song,Z.Tang,D.Zhang,X.Wen,S.Lv,Z.Liu,M.Deng,X.Chen,SolidTumorTherapyUsingaCannonandPawnCombinationStrategy,Theranostics6(7)(2016)1023-1030.[6]W.Song,Z.Tang,D.Zhang,M.Li,J.Gu,X.Chen,Acooperativepolymericplatformfortumor-targeteddrugdelivery,ChemicalScience7(1)(2016)728-736.[7]W.Song,Z.Tang,N.Shen,H.Yu,Y.Jia,D.Zhang,J.Jiang,C.He,H.Tian,X.Chen,Combiningdisulfiramandpoly(l-glutamicacid)-cisplatinconjugatesforcombatingcisplatinresistance,J.Control.Release231(2016)94-102.[8]W.Song,Z.Tang,T.Lei,X.Wen,G.Wang,D.Zhang,M.Deng,X.Tang,X.Chen,StableloadinganddeliveryofdisulfiramwithmPEG-PLGA/PCLmixednanoparticlesfortumortherapy,Nanomed.Nanotechnol.Biol.Med.12(2)(2016)377-86.[9]Y.Niu,W.Song,D.Zhang,Z.Tang,M.Deng,X.Chen,Functionalcomputer-to-platenear-infraredabsorbersashighlyefficientphotoacousticdyes,ActaBiomater.43(2016)262-8.[10]C.He,Z.Tang,H.Tian,X.Chen,Co-deliveryofchemotherapeuticsandproteinsforsynergistictherapy,Adv.DrugDel.Rev.98(2016)64-76.[11]J.Chen,L.Lin,Z.Guo,C.Xu,Y.Li,H.Tian,Z.Tang,C.He,X.Chen,N-IsopropylacrylamideModifiedPolyethyleniminesasEffectivesiRNACarriersforCancerTherapy,JournalofNanoscienceandNanotechnology16(6)(2016)5464-5469.[12]Z.Ahmad,S.Lv,Z.Tang,A.Shah,X.Chen,Methoxypoly(ethyleneglycol)-block-poly(glutamicacid)-graft-6-(2-nitroimidazole)hexylaminenanoparticlesforpotentialhypoxia-responsivedeliveryofdoxorubicin,J.Biomater.Sci.Polym.Ed.27(1)(2016)40-54.[13]马丽莉,邵俊,杨晨光,汤朝晖,陈学思,PDLA-PBS-PDLA三嵌段共聚物的合成及性能,高等学校化学学报36(11)(2015)2329-2334.[14]H.Yu,Z.Tang,D.Zhang,W.Song,Y.Zhang,Y.Yang,Z.Ahmad,X.Chen,Pharmacokinetics,biodistributionandinvivoefficacyofcisplatinloadedpoly(L-glutamicacid)-g-methoxypoly(ethyleneglycol)complexnanoparticlesfortumortherapy,J.Control.Release205(2015)89-97.[15]H.Yu,Z.Tang,D.Zhang,W.Song,T.Duan,J.Gu,X.Chen,Poly(ornithine‐co‐arginine‐co‐glycine‐co‐asparticAcid):PreparationviaNCAPolymerizationanditsPotentialasaPolymericTumor‐PenetratingAgent,Macromol.Biosci.15(6)(2015)829–838.[16]H.Yu,Z.Tang,W.Song,D.Zhang,Y.Zhang,X.Chen,Co-administrationofiRGDenhancingtheanticancerefficacyofcisplatin-loadedpolypeptidenanoparticles,J.Control.Release213(2015)e145-e146.[17]H.Y.YifeiLi,HaiSun,JianguoLiu,ZhaohuiTang,DanWang,LianyouYu,XuesiChen,Cisplatin-loadedpoly(L-glutamicacid)-g-methoxypoly(ethyleneglycol)nanoparticlesasapotentialchemotherapeuticagentagainstosteosarcoma,Chin.J.Polym.Sci.33(5)(2015)763-771.[18]W.Song,Z.Tang,D.Zhang,H.Yu,X.Chen,CoadministrationofVascularDisruptingAgentsandNanomedicinestoEradicateTumorsfromPeripheralandCentralRegions,Small11(31)(2015)3755-3761.[19]W.Song,Z.Tang,D.Zhang,N.Burton,W.Driessen,X.Chen,Comprehensivestudiesofpharmacokineticsandbiodistributionofindocyaninegreenandliposomalindocyaninegreenbymultispectraloptoacoustictomography,RSCAdv.5(5)(2015)3807-3813.[20]C.Shi,H.Yu,D.Sun,L.Ma,Z.Tang,Q.Xiao,X.Chen,Cisplatin-loadedpolymericnanoparticles:Characterizationandpotentialexploitationforthetreatmentofnon-smallcelllungcarcinoma,ActaBiomater.18(2015)68–76.[21]M.Q.Li,Z.H.Tang,Y.Zhang,S.X.Lv,Q.S.Li,X.S.Chen,TargeteddeliveryofcisplatinbyLHRH-peptideconjugateddextrannanoparticlessuppressesbreastcancergrowthandmetastasis,ActaBiomater.18(2015)132-143.[22]M.Li,Z.Tang,D.Zhang,H.Sun,H.Liu,Y.Zhang,Y.Zhang,X.Chen,Doxorubicin-loadedpolysaccharidenanoparticlessuppressthegrowthofmurinecolorectalcarcinombbndinhibitthemetastasisofmurinemammarycarcinomainrodentmodels,Biomaterials51(0)(2015)161-172.[23]B.Feng,Z.Xu,F.Zhou,H.Yu,Q.Sun,D.Wang,Z.Tang,H.Yu,Q.Yin,Z.Zhang,Y.Li,Nearinfraredlight-actuatedgoldnanorodswithcisplatin-polypeptidewrappingfortargetedtherapyoftriplenegativebreastcancer,Nanoscale7(36)(2015)14854-64.[24]R.Zhao,X.Li,B.Sun,Y.Zhang,D.Zhang,Z.Tang,X.Chen,C.Wang,Electrospunchitosan/sericincompositenanofiberswithantibacterialpropertyaspotentialwounddressings,Int.J.Biol.Macromol.68(2014)92-97.[25]H.Yu,Z.Tang,W.Song,M.Deng,X.Chen,CurrentStatusandFutureProspectsofPolymericNanocarrierforTumorTargeting,Chem.J.Chin.Univ.-Chin.35(5)(2014)903-916.[26]W.Song,Z.Tang,D.Zhang,Y.Zhang,H.Yu,M.Li,S.Lv,H.Sun,M.Deng,X.Chen,Anti-tumorefficacyofc(RGDfK)-decoratedpolypeptide-basedmicellesco-loadedwithdocetaxelandcisplatin,Biomaterials35(9)(2014)3005-3014.[27]W.Song,Z.Tang,M.Li,S.Lv,H.Sun,M.Deng,H.Liu,X.Chen,Polypeptide-basedcombinationofpaclitaxelandcisplatinforenhancedchemotherapyefficacyandreducedside-effects,ActaBiomater.10(3)(2014)1392-1402.[28]J.Shao,Z.Tang,J.Sun,G.Li,X.Chen,LinearandFour-ArmedPoly(L-lactide)-block-poly(D-lactide)CopolymersandTheirStereocomplexationwithPoly(lactide)s,JournalofPolymerSciencePartB-PolymerPhysics52(23)(2014)1560-1567.[29]Z.Qu,R.Duan,X.Pang,B.Gao,X.Li,Z.Tang,X.Wang,X.Chen,LivingandStereoselectivePolymerizationofRac-LactidebyBimetallicAluminumSchiff-BaseComplexes,JournalofPolymerScienceParta-PolymerChemistry52(9)(2014)1344-1352.[30]S.Lv,Z.Tang,D.Zhang,W.Song,M.Li,J.Lin,H.Liu,X.Chen,Well-definedpolymer-drugconjugateengineeredwithredoxandpH-sensitivereleasemechanismforefficientdeliveryofpaclitaxel,J.Control.Release194(2014)220-227.[31]S.Lv,Z.Tang,M.Li,J.Lin,W.Song,H.Liu,Y.Huang,Y.Zhang,X.Chen,Co-deliveryofdoxorubicinandpaclitaxelbyPEG-polypeptidenanovehicleforthetreatmentofnon-smallcelllungcancer,Biomaterials35(23)(2014)6118-6129.[32]S.Lv,W.Song,Z.Tang,M.Li,H.Yu,H.Hong,X.Chen,Charge-ConversionalPEG-PolypeptidePolyionicComplexNanoparticlesfromSimpleBlendingofaPairofOppositelyChargedBlockCopolymersasanIntelligentVehicleforEfficientAntitumorDrugDelivery,Mol.Pharm.11(5)(2014)1562-1574.[33]Q.Li,S.Lv,Z.Tang,M.Liu,D.Zhang,Y.Yang,X.Chen,Aco-deliverysystembasedonpaclitaxelgraftedmPEG-b-PLGloadedwithdoxorubicin:Preparation,invitroandinvivoevaluation,Int.J.Pharm.471(1–2)(2014)412-420.[34]M.-q.Li,Z.-h.Tang,C.Wang,Y.Zhang,H.-t.Cui,X.-s.Chen,Efficientside-chainmodificationofdextranviabase-catalyzedepoxidering-openingandthiol-eneclickchemistryinaqueousmedia,Chin.J.Polym.Sci.32(8)(2014)969-974.[35]M.Li,Z.Tang,Y.Zhang,S.Lv,H.Yu,D.Zhang,H.Hong,X.Chen,LHRH-peptideconjugateddextrannanoparticlesfortargeteddeliveryofcisplatintobreastcancer,J.Mat.Chem.B2(22)(2014)3490-3499.[36]M.Li,Z.Tang,S.Lv,W.Song,H.Hong,X.Jing,Y.Zhang,X.Chen,CisplatincrosslinkedpH-sensitivenanoparticlesforefficientdelivery.ofdoxorubicin,Biomaterials35(12)(2014)3851-3864.[37]M.Li,Z.Tang,J.Lin,Y.Zhang,S.Lv,W.Song,Y.Huang,X.Chen,SynergisticAntitumorEffectsofDoxorubicin-LoadedCarboxymethylCelluloseNanoparticleinCombinationwithEndostarforEffectiveTreatmentofNon-Small-CellLungCancer,Adv.Healthc.Mater.3(11)(2014)1877-1888.[38]Z.Guo,H.Tian,L.Lin,J.Chen,C.He,Z.Tang,X.Chen,HydrophobicPolyalanineModifiedHyperbranchedPolyethylenimineasHighEfficientpDNAandsiRNACarrier,Macromol.Biosci.14(10)(2014)1406-1414.[39]J.Chen,J.Xia,H.Tian,Z.Tang,C.He,X.Chen,Thermo-/pH-dualresponsivepropertiesofhyperbranchedpolyethyleniminegraftedbyphenylalanine,Arch.Pharm.Res.37(1)(2014)142-148.[40]Z.Ahmad,Z.Tang,A.Shah,S.Lv,D.Zhang,Y.Zhang,X.Chen,CisplatinLoadedMethoxyPoly(ethyleneglycol)-block-Poly(L-glutamicacid-co-L-Phenylalanine)NanoparticlesagainstHumanBreastCancerCell,Macromol.Biosci.14(9)(2014)1337-1345.[41]L.Zhao,C.Xiao,J.Ding,P.He,Z.Tang,X.Pang,X.Zhuang,X.Chen,Facileone-potsynthesisofglucose-sensitivenanogelviathiol-eneclickchemistryforself-regulateddrugdelivery,ActaBiomater.9(5)(2013)6535-6543.[42]L.Zhao,J.Ding,C.Xiao,P.He,Z.Tang,X.Chen,Phenylboronicacidfunctionalizedpolypeptidemicellesforglucose-responsiveinsulinreleaseatphysiologicalpH,J.Control.Release172(1)(2013)E110-E110.[43]S.Lv,M.Li,Z.Tang,W.Song,H.Sun,H.Liu,X.Chen,Doxorubicin-loadedamphiphilicpolypeptide-basednanoparticlesasanefficientdrugdeliverysystemforcancertherapy,ActaBiomater.9(12)(2013)9330-9342.[44]M.Li,Z.Tang,H.Sun,J.Ding,W.Song,X.Chen,pHandreductiondual-responsivenanogelcross-linkedbyquaternizationreactionforenhancedcellularinternalizationandintracellulardrugdelivery,Polym.Chem.4(4)(2013)1199-1207.[45]M.Li,W.Song,Z.Tang,S.Lv,L.Lin,H.Sun,Q.Li,Y.Yang,H.Hong,X.Chen,NanoscaledPoly(L-glutamicacid)/Doxorubicin-AmphiphileComplexaspH-responsiveDrugDeliverySystemforEffectiveTreatmentofNonsmallCellLungCancer,AcsAppliedMaterials&Interfaces5(5)(2013)1781-1792.[46]M.Li,S.Lv,Z.Tang,W.Song,H.Yu,H.Sun,H.Liu,X.Chen,Polypeptide/DoxorubicinHydrochloridePolymersomesPreparedThroughOrganicSolvent-freeTechniqueasaSmartDrugDeliveryPlatform,Macromol.Biosci.13(9)(2013)1150-1162.[47]D.Li,H.Sun,J.Ding,Z.Tang,Y.Zhang,W.Xu,X.Zhuang,X.Chen,Polymerictopologyandcompositionconstrainedpolyether-polyestermicellesfordirectionalantitumordrugdelivery,ActaBiomater.9(11)(2013)8875-8884.[48]Y.Huang,Z.Tang,X.Zhang,H.Yu,H.Sun,X.Pang,X.Chen,pH-TriggeredCharge-ReversalPolypeptideNanoparticlesforCisplatinDelivery:PreparationandInVitroEvaluation,Biomacromolecules14(6)(2013)2023-2032.[49]P.He,C.-w.Zhao,C.-s.Xiao,Z.-h.Tang,X.-s.Chen,Thermosensitivepolyioncomplexmicellespreparedbyself-assemblyoftwooppositelychargeddiblockcopolymers,Chin.J.Polym.Sci.31(2)(2013)318-324.[50]P.He,H.Liu,Z.Tang,M.Deng,Y.Yang,X.Pang,X.Chen,Poly(esteramide)blendmicrospheresfororalinsulindelivery,Int.J.Pharm.455(1-2)(2013)259-266.[51]C.He,Z.Tang,H.Tian,X.Chen,ProgressintheDevelopmentofBiomedicalPolymerMaterialsFabricatedby3-DimensionalPrintingTechnology,ActaPolymericaSinica(6)(2013)722-732.[52]J.Guo,X.Li,H.Yu,Z.Tang,X.Tang,C.Cai,J.Xu,H.Xu,Theanti-melanomaefficiencyoftheintratumoralinjectionofcucurbitacin-loadedsustained-releasecarriers:APLGAparticlesystem,J.Pharm.Sci.102(8)(2013)2550-2563.[53]B.Gao,R.Duan,X.Pang,X.Li,Z.Qu,Z.Tang,X.Zhuang,X.Chen,StereoselectiveRing-OpeningPolymerizationofrac-LactidesCatalyzedbyAluminumHemi-SalenComplexes,Organometallics32(19)(2013)5435-5444.[54]L.Zhao,J.Ding,C.Xiao,P.He,Z.Tang,X.Pang,X.Zhuang,X.Chen,Glucose-sensitivepolypeptidemicellesforself-regulatedinsulinreleaseatphysiologicalpH,J.Mater.Chem.22(24)(2012)12319-12328.[55]H.Tian,Z.Tang,X.Zhuang,X.Chen,X.Jing,Biodegradablesyntheticpolymers:Preparation,functionalizationandbiomedicalapplication,Prog.Polym.Sci.37(2)(2012)237-280.[56]W.Song,C.Xiao,L.Cui,Z.Tang,X.Zhuang,X.Chen,FacileconstructionoffunctionalbiosurfaceviaSI-ATRPand"clickglycosylation",ColloidSurf.B-Biointerfaces93(2012)188-194.[57]W.Song,Z.Tang,M.Li,S.Lv,H.Yu,L.Ma,X.Zhuang,Y.Huang,X.Chen,TunablepH-SensitivePoly(beta-aminoester)sSynthesizedfromPrimaryAminesandDiacrylatesforIntracellularDrugDelivery,Macromol.Biosci.12(10)(2012)1375-1383.[58]W.Song,M.Li,Z.Tang,Q.Li,Y.Yang,H.Liu,T.Duan,H.Hong,X.Chen,Methoxypoly(ethyleneglycol)-block-Poly(L-glutamicacid)-LoadedCisplatinandaCombinationWithiRGDfortheTreatmentofNon-Small-CellLungCancers,Macromol.Biosci.12(11)(2012)1514-1523.[59]D.Li,J.X.Ding,Z.H.Tang,H.Sun,X.L.Zhuang,J.Z.Xu,X.S.Chen,InvitroevaluationofanticancernanomedicinesbasedondoxorubicinandamphiphilicY-shapedcopolymers,Int.J.Nanomedicine7(2012)2687-2697.[60]P.He,Z.Tang,L.Lin,M.Deng,X.Pang,X.Zhuang,X.Chen,NovelBiodegradableandpH-SensitivePoly(esteramide)MicrospheresforOralInsulinDelivery,Macromol.Biosci.12(4)(2012)547-556.[61]C.He,X.Zhuang,Z.Tang,H.Tian,X.Chen,Stimuli-SensitiveSyntheticPolypeptide-BasedMaterialsforDrugandGeneDelivery,Adv.Healthc.Mater.1(1)(2012)48-78.[62]汤朝晖,陈学思,新型药控/缓释材料,中国新材料产业发展报告（2010）2011.[63]X.-l.Zhuang,H.-y.Yu,Z.-h.Tang,K.Oyaizu,H.Nishide,X.-s.Chen,PolymerizationoflacticO-carboxylicanhydrideusingorganometalliccatalysts,Chin.J.Polym.Sci.29(2)(2011)197-202.[64]L.Zhao,J.Ding,P.He,C.Xiao,Z.Tang,X.Zhuang,X.Chen,AnefficientpHsensitiveoralinsulindeliverysystemenhancedbydeoxycholicacid,J.Control.Release152(2011)E184-E186.[65]W.Wang,J.Ding,C.Xiao,Z.Tang,D.Li,J.Chen,X.Zhuang,X.Chen,SynthesisofAmphiphilicAlternatingPolyesterswithOligo(ethyleneglycol)SideChainsandPotentialUseforSustainedReleaseDrugDelivery,Biomacromolecules12(7)(2011)2466-2474.[66]J.Ding,X.Zhuang,C.Xiao,Y.Cheng,L.Zhao,C.He,Z.Tang,X.Chen,Preparationofphoto-cross-linkedpH-responsivepolypeptidenanogelsaspotentialcarriersforcontrolleddrugdelivery,J.Mater.Chem.21(30)(2011)11383-11391.[67]J.Ding,C.Xiao,L.Zhao,Y.Cheng,L.Ma,Z.Tang,X.Zhuang,X.Chen,Poly(L-glutamicacid)GraftedwithOligo(2-(2-(2-methoxyethoxy)ethoxy)ethylmethacrylate):ThermalPhaseTransition,SecondaryStructure,andSelf-Assembly,JournalofPolymerScienceParta-PolymerChemistry49(12)(2011)2665-2676.[68]J.Ding,C.Xiao,L.Yan,Z.Tang,X.Zhuang,X.Chen,X.Jing,pHanddualredoxresponsivenanogelbasedonpoly(l-glutamicacid)aspotentialintracellulardrugcarrier,J.Control.Release152(2011)E11-E13.[69]J.Ding,C.Xiao,Z.Tang,X.Zhuang,X.Chen,HighlyEfficient"GraftingFrom"analpha-HelicalPolypeptideBackbonebyAtomTransferRadicalPolymerization,Macromol.Biosci.11(2)(2011)192-198.[70]C.Xiao,C.Zhao,P.He,Z.Tang,X.Chen,X.Jing,FacileSynthesisofGlycopolypeptidesbyCombinationofRing-OpeningPolymerizationofanAlkyne-SubstitutedN-carboxyanhydrideandClick"Glycosylation",Macromol.RapidCommun.31(11)(2010)991-997.[71]F.Wan,Z.Tang,W.He,B.Chu,Achemistry/physicspathwaywithnanofibrousscaffoldsforgenedelivery,PCCP12(39)(2010)12379-12389.[72]X.Pang,X.Zhuang,Z.Tang,X.Chen,Polylacticacid(PLA):Research,developmentandindustrialization,BiotechnologyJournal5(11)(2010)1125-1136.[73]Z.H.Tang,C.Q.Qiu,J.R.McCutcheon,K.Yoon,H.Y.Ma,D.F.Fang,E.Lee,C.Kopp,B.S.Hsiao,B.Chu,DesignandFabricationofElectrospunPolyethersulfoneNanofibrousScaffoldforHigh-FluxNanofiltrationMembranes,JournalofPolymerSciencePartB-PolymerPhysics47(22)(2009)2288-2300.[74]Z.Tang,J.Wei,L.Yung,B.Ji,H.Ma,C.Qiu,K.Yoon,F.Wan,D.Fang,B.S.Hsiao,B.Chu,UV-curedpoly(vinylalcohol)ultrafiltrationnanofibrousmembranebasedonelectrospunnanofiberscaffolds,J.Membr.Sci.328(1-2)(2009)1-5.[75]Z.Tang,V.C.Gibson,rac-Lactidepolymerizationusingaluminumcomplexesbearingtetradentatephenoxy-amineligands,Eur.Polym.J.43(1)(2007)150-155.[76]Y.K.Yang,Z.H.Tang,X.Pang,H.Z.Du,X.S.Chen,X.B.Jing,Stereoselectivepolymerizationofrac-lactideinitiatedbyachiralSchiff-baseisopropoxidealuminumcomplex,Chem.J.Chin.Univ.-Chin.27(2)(2006)352-355.[77]Z.Tang,X.Pang,J.Sun,H.Du,X.Chen,Five-coordinatedactivespeciesinthestereoselectivepolymerizationofrac-lactideusingN,N'-(2,2-dimethyl-1,3-propylene)bis(3,5-di-tert-butyl-salicylideneimine)aluminumcomplexes,JournalofPolymerScienceParta-PolymerChemistry44(16)(2006)4932-4938.[78]Z.H.Tang,Y.K.Yang,X.Pang,J.L.Hu,X.S.Chen,N.H.Hu,X.B.Jing,Controlledandstereospecificpolymerizationofrac-lactidewithasingle-siteethylaluminumandalcoholinitiatingsystem,J.Appl.Polym.Sci.98(1)(2005)102-108.[79]J.L.Hu,Z.H.Tang,X.Y.Qiu,X.Pang,Y.K.Yang,X.S.Chen,X.B.Jing,Formationofflower-orcake-shapedstereocomplexparticlesfromthestereomultiblockcopoly(rac-lactide)s,Biomacromolecules6(5)(2005)2843-2850.[80]J.Hu,Z.Tang,X.Qiu,Y.Han,Q.Du,X.Chen,X.Jing,EffectsofStereoregularityofMultiblockCopoly(rac-lactide)sonStereocomplexMicroparticlesandTheirInsulinDelivery,Macromol.Biosci.5(12)(2005)1193-1199.[81]H.L.Guan,Z.G.Xie,Z.H.Tang,X.Y.Xu,X.S.Chen,X.B.Jing,Preparationofblockcopolymerofepsilon-caprolactoneand2-methyl-2-carboxyl-propylenecarbonate,Polymer46(8)(2005)2817-2824.[82]C.Deng,G.Z.Rong,H.Y.Tian,Z.H.Tang,X.S.Chen,X.B.Jing,Synthesisandcharacterizationofpoly(ethyleneglycol)-b-poly(L-lactide)-b-poly(L-glutamicacid)triblockcopolymer,Polymer46(3)(2005)653-659.[83]Z.H.Tang,X.S.Chen,Y.K.Yang,X.Pang,J.R.Sun,X.F.Zhang,X.B.Jing,Stereoselectivepolymerizationofrac-lactidewithabulkyaluminum/Schiffbasecomplex,JournalofPolymerScienceParta-PolymerChemistry42(23)(2004)5974-5982.[84]Z.H.Tang,X.S.Chen,X.Pang,Y.K.Yang,X.F.Zhang,X.B.Jing,Stereoselectivepolymerizationofrac-lactideusingamonoethylaluminumSchiffbasecomplex,Biomacromolecules5(3)(2004)965-970.[85]J.R.Sun,Z.K.Hong,L.X.Yang,Z.H.Tang,X.S.Chen,X.B.Jing,Studyoncrystallinemorphologyofpoly(L-lactide)-poly(ethyleneglycol)diblockcopolymer,Polymer45(17)(2004)5969-5977.[86]Z.H.Tang,X.S.Chen,Q.Z.Hang,X.C.Bian,L.X.Yang,L.H.Piao,X.B.Jing,Strontium-basedinitiatorsystemforring-openingpolymerizationofcyclicesters,JournalofPolymerScienceParta-PolymerChemistry41(13)(2003)1934-1941.[87]G.Z.Rong,M.X.Deng,C.Deng,Z.H.Tang,L.H.Piao,X.S.Chen,X.B.Jing,Synthesisofpoly(epsilon-caprolactone)-b-poly(gamma-benzyl-L-glutamicacid)blockcopolymerusingaminoorganiccalciumcatalyst,Biomacromolecules4(6)(2003)1800-1804.专利目录（部分）1. 汤朝晖；孙环娇；于海洋；吕世贤；张大为；陈学思一种高分子抗肿瘤前药及其制备方法.CN201410417521.7,2014.2. 汤朝晖;李明强;于海洋;宋万通;陈学思改性聚多糖及其制备方法.CN201410133893.7,2014.3. 汤朝晖;李明强;林坚;宋万通;陈学思聚多巴胺纳米粒子的应用.CN201410177537.5,2014.4. 汤朝晖;李明强;高中辉;于海洋;陈学思一种聚苯胺纳米粒子的制备方法及其应用.CN201410177564.2,2014.5. 汤朝晖；于海洋；宋万通；李明强；陈学思阿霉素复合物及其制备方法.CN201310002466.0,2013.6. 汤朝晖；宋万通；于海洋；李明强；陈学思二氯-1,2-环己二胺合铂配合物及其制备方法.CN201310361430.1,2013.7. 汤朝晖；吕世贤；陈学思；李明强；宋万通；于海洋氨基酸嵌段共聚物及其制备方法和复合物.CN201310009638.7,2013.8. 汤朝晖；李明强；宋万通；陈学思一种二价双核铂配合物及其制备方法.CN201310361461.7,2013.9. 汤朝晖；李明强；陈学思；张影乙二胺四乙酸双核铂配合物及其制备方法.CN201310449569.1,2013.10. 汤朝晖;李雪;于海洋;张大为;宋万通;陈学思一种创伤止血敷料的制备方法.CN201310547279.0,2013.11. 汤朝晖;李明强;林坚;宋万通;吕世贤;陈学思共担载顺铂和阿霉素的复合物、胶束及胶束的制备方法.CN201310039396.6,2013.12. 孙海;汤朝晖;许午;高战团;庄秀丽;陈学思一种紫杉醇高分子键合药及其制备方法.CN201310588848.6,2013.13. 汤朝晖;于海洋;宋万通;李明强;庄秀丽;陈学思顺铂配合物及其制备方法.CN201210382696.X,2012.14. 汤朝晖;宋万通;吕世贤;于海洋;陈学思一种聚乙二醇-聚β-胺酯嵌段共聚物及其制备方法.CN201210311209.0,2012.15. 汤朝晖;宋万通;李明强;丁建勋;于海洋;陈学思一种聚氨基酸接枝共聚物及其制备方法.CN201210391089.X,2012.16. 汤朝晖;李明强;宋万通;吕世贤;陈学思;庄秀丽阿霉素纳米粒及其制备方法.CN201210034414.7,2012.17. 汤朝晖;李明强;宋万通;丁建勋;陈学思;庄秀丽阿霉素复合物、胶束及胶束的制备方法.CN201210034443.3,2012.18. 汤朝晖;李明强;宋万通;陈学思;陈杰;庄秀丽顺铂配合物及其制备方法.CN201210034430.6,2012.19. 汤朝晖;黄月;陈学思一种顺铂配合物及其制备方法.CN201210430624.8,2012.20. 陈学思;赵丽;肖春生;丁建勋;何盼;汤朝晖聚合物、葡萄糖纳米凝胶、葡萄糖纳米凝胶组合物及其制备方法.CN201210512665.1,2012.21. 庄秀丽;丁建勋;肖春生;贺超良;汤朝晖;陈学思聚氨基酸接枝共聚物及其制备方法.CN201110023705.1,2011.22. 庄秀丽;丁建勋;栗迪;汤朝晖;陈学思聚氨基酸嵌段共聚物及其制备方法.CN201110343619.9,2011.23. 汤朝晖;赵丽;丁建勋;肖春生;何盼;陈学思共聚物、葡萄糖敏感胶束、葡萄糖敏感载药胶束及其制备方法.CN201110260560.7,2011.24. 汤朝晖;赵丽;丁建勋;何盼;肖春生;庄秀丽;陈学思一种胰岛素载药微球及其制备方法.CN201110023708.5,2011.25. 汤朝晖;栗迪;丁建勋;孙海;庄秀丽;陈学思嵌段共聚物及其制备方法.CN201110325770.X,2011.26. 汤朝晖;栗迪;丁建勋;孙海;庄秀丽;陈学思抗肿瘤前药及其制备方法.CN201110149748.4,2011.27. 陈学思;何盼;汤朝晖;庄秀丽;林琳胰岛素载药微球及其制备方法.CN201110368851.8,2011.28. 庄秀丽;高晓晔;汤朝晖;陈学思一种聚(L-谷氨酸)/聚丙烯酸水凝胶及其制备方法.CN201010130914.1,2010.29. 庄秀丽;丁建勋;赵丽;肖春生;汤朝晖;陈学思一种聚合物微凝胶及其制备方法.CN201010130890.X,2010.30. 庄秀丽;丁建勋;肖春生;成一龙;赵丽;汤朝晖;陈学思聚（L-谷氨酸）均聚物、无规共聚物、接枝共聚物及其制备方法.CN201010563665.5,2010.31. 庄秀丽;丁建勋;汤朝晖;陈学思一种功能化聚酯及其制备方法.CN201010130905.2,2010.32. 庄秀丽;丁建勋;汤朝晖;陈学思聚合物纳米水凝胶及其制备方法.CN201010561226.0,2010.33. 庄秀丽;丁建勋;高晓晔;肖春生;汤朝晖;陈学思聚合物纳米水凝胶及其制备方法.CN201010563357.2,2010.34. 庄秀丽;丁建勋;肖春生;赵长稳;汤朝晖;陈学思氯乙醇功能化聚(L-谷氨酸)均聚与无规共聚物及制法和应用.CN200910218013.5,2009.
研究方向 Researchdirection1、生物医用高分子材料2、药物缓控释高分子载体3、纳米药物